الكاتب: Multiple References

metabolic changesBenzodiazepines have been used in horses combined with a-2 agonists, tiletamine, ketamine and guaiphenesin (Rehm & Schatzmann, 1984; Hubbell et al., 1989; Matthews et al., 1991; Luna et al., 1992). These combinations produced recumbency rapidly and smoothly, cardiorespiratory depression was mild, but in some studies recovery was long and unsatisfactory (Hubbell et al., 1989). Luna et al. (1992) obtained a rapid and smooth induction and stable cardiorespiratory function during anaesthesia employing a combination of methotrimeprazine, guaiphenesin and midazolam for induction before halothane anaesthesia in horses. The addition of ketamine to this combination also resulted in quicker recovery from anaesthesia. Midazolam, due its shorter duration of effect than most benzodiazepines, appears to have potential for use in horses. Also midazolam might be beneficial in reducing the endocrine stress response to anaesthesia observed in horses (Luna & Taylor, 1995).