الكاتب: Multiple References

The lincosamides have activity against many gram-positive bacteria and many anaerobic bacteria, but are not effective against most gram-negative organisms. Lincomycin has been shown to have efficacy against Erysipelothrix insidiosa, Leptospira pomona, Mycoplasma species, Staphylococcus species, and Streptococcus species (except Streptococcus faecalis).{R-3; 4} The activity of lincomycin against obligate anaerobes is seldom addressed in published literature; one exception is in vitro activity against Fusobacterium necrophorum. {R-60} According to the National Committee for Clinical Laboratory Standards in the United States, clindamycin is the class antibiotic for the lincosamide family and the clindamycin disk is used in in vitro testing to assess susceptibility to both clindamycin and lincomycin.{R-31} Therefore, it is presumed that most anaerobes susceptible to clindamycin would likewise be susceptible to lincomycin, provided compensations for potency and kinetic disposition are made.{R-39} Clindamycin has a spectrum of activity that includes Mycoplasma species, Staphylococcus species, and Streptococcus species (except Streptococcus faecalis), as well as anaerobic organisms, such as Actinomyces species, Bacteroides species, Clostridium perfringens (but not necessarily other clostridia), Fusobacterium species, Peptostreptococcus species, and many Propionibacterium species.