الكاتب: Multiple References

The fluoroquinolone class of compounds includes many extremely potent, broad-spectrum antimicrobial agents with excellent activity against many gram-negative bacteria (16). This class of antimicrobial agents has shown excellent in vitro activity against Escherichia coli clinical isolates of human origin (6, 15), including enterotoxigenic E. coli (3, 5, 12), and many have been used successfully in the prevention and treatment of traveler's diarrhea (4, 9). In veterinary medicine, fluoroquinolones have been introduced recently and few reports about their in vitro activities against bacterial clinical isolates of animal origin exist (11). In this report, we describe the results of in vitro activities of four fluoroquinolone compounds (enoxacin, enrofloxacin, sparfloxacin, and ciprofloxacin) against E. coli strains isolated from lambs and kids affected by neonatal diarrhea