الكاتب: Multiple References

Florfenicol (FFC), a fluorinated chloramphenicol derivative, is exclusively used in veterinary medicine. So far, its use in food-producing animals—exclusive of aquaculture—has been limited to cattle and swine. FFC was licensed as an injectable drug only for the treatment of bovine and porcine respiratory tract infections in 1995 and 2000, respectively. The main target bacteria in cattle are Pasteurella multocida, Mannheimia haemolytica, and Haemophilus somnus, whereas those in pigs are P. multocida, Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, and Streptococcus suis. The aim of this study was to monitor the in vitro susceptibilities to FFC of bovine respiratory pathogens at 5 to 6 years after the introduction of FFC and those of porcine respiratory pathogens at the time of introduction of FFC into clinical veterinary use.