Evaluation of the effect of ketoprofen on experimentally induced ephemeral fever in dairy heifers

كتاب Evaluation of the effect of ketoprofen on experimentally induced ephemeral fever in dairy heifers


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Ephemeral fever in cattle was reviewed by Uren (1989) who claimed that it is arguably the most important viral disease of cattle in Australia. It is endemic to extensive areas of Australia from Queensland to northern Victoria. Although 99% of affected animals recover spontaneously, it has been estimated to cause losses of millions of dollars annually in beef and dairy cattle. These losses are due to loss of weight, temporary sterility of bulls, abortions, decline in lactation and deaths. Mortality is estimated at 1%. Phenylbutazone, acetylsalicylic acid, flunixin meglimine, tripelennamine, butophosphan and tylosin have been used empirically as treatments, but evaluation of their effectiveness has been limited and of doubtful value (Hungerford 1990). Intravenous calcium solutions have also been recommended (Uren 1989). There is a need for evaluation of new drugs for treatment of this disease. This paper records the effects of ketoprofen on heifers infected experimentally with ephemeral fever.



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