الكاتب: Multiple References

The disposition kinetics and dosage regimen of cephaloridine were investigated in calves following a single intravenous dose of 10 mg •k g ' . The distribution half-life and elimination half-life were 0-16±0-02 and 1-96±0-16h, respectively. The apparent volume of distribution was 0-64±0-06 1-kg -1 and total body clearance which represents the sum of all clearance processes, was 225 . 2 ± 15 . 1 ml • kg-1 • h-' . Based on kinetic parameters, a satisfactory intravenous dosage regimen of cephaloridine in calves would be 11 . 0 mg-kg-1 repeated every 8 h