الكاتب: Multiple References

Contagious bovine pleuropneumonia (CBPP), an Office International des Epizooties-listed disease, is caused by Mycoplasma mycoides subsp. mycoides small-colony type (MmmSC). In Africa the disease is widespread and threatens to extend into areas where it is currently not found. Control of the disease is difficult, but Botswana, Portugal, and Italy have relatively recently eradicated the disease. These successful campaigns relied on effective diagnosis, slaughter, and compensation methods. The only other method is vaccination with a live attenuated strain, T1/44, which offers short-term immunity, but can cause adverse reactions and even CBPP itself (6). Development of alternative vaccines has been unsuccessful, often resulting in exacerbation of disease (9). Treatment of affected cattle with antimicrobials is officially discouraged, although in many African countries it is widely practiced (5). Previously it has been reported that antimicrobial treatment may alleviate the clinical signs, but not prevent the spread of infection, and may favor the creation of chronic carriers (10). However, one recent recommendation was that research should be conducted on the activity of new antimicrobials in controlling CBPP