الكاتب: Multiple References

The aminopenicillins have activity against penicillin-sensitive grampositive bacteria as well as some gram-negative bacteria. Ampicillin is effective against alpha- and beta-hemolytic streptococci, including Streptococcus equi,{R-1} non–penicillinaseproducing Staphylococcus species, some Bacillus anthracis, and most strains of Clostridia. {R-3} Ampicillin is also effective against gram-negative bacteria, including many strains of Escherichia coli (E. coli), Salmonella, and Pasteurella multocida.{R-3} Amoxicillin has the same spectrum of activity as ampicillin, but has slightly better activity against some gram-negative bacteria, including E. coli, and Salmonella species.{R-4} Most anaerobic bacteria, except beta-lactamase–producing strains of Bacteroides, are sensitive to amoxicillin.{R-78} The aminopenicillins are subject to destruction by beta-lactamases and therefore are not effective against some bacteria that produce these enzymes.{R-1; 3} Most strains of Klebsiella, Proteus, and Pseudomonas are resistant.