AN EXAMPLE OF THE INFLUENCE OF PHENYLBUTAZONE ON ENDOTOXEMIA AND THE CLINICAL PICTURE OF JEJUNAL COMPLICATIONS IN HORSES

كتاب AN EXAMPLE OF THE INFLUENCE OF PHENYLBUTAZONE ON ENDOTOXEMIA AND THE CLINICAL PICTURE OF JEJUNAL COMPLICATIONS IN HORSES


الكاتب: Multiple References

During a clinical examination of a stallion on the day after a race, symptoms were established that could not be logically connected, so a more extensive examination and treatment at our clinic were proposed. A blood sample showed changed blood parameter values. The stallion was brought to the clinic five hours later. On the basis of the clinical picture, intestinal complications were suspected, but the horse’s condition did not improve even after an opioid analgesic and supportive therapy were administered. The stallion died only one hour after arriving at the clinic. The pathological, histological and toxicological examination showed complications: jejunal necrosis and ulcers, pulmonary edema and a dilated heart, the failure of which was the immediate cause of the horse’s death. Toxicological analysis showed the presence of phenylbutazone in the blood. This masked the clinical picture of endotoxemia which had a decisive effect on the damage to the heart and its failure. Immediately before arriving at our clinic, the stallion also received an infusion of calcium preparations, which had an additional toxic effect on the already weakened heart.



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